Recent Publications

Articles

• The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase–LRP4 receptor complex by agrin at the neuromuscular junction
  Thi Minh Uyen Dao, Susie Barbeau, Julien Messéant, Bruno Della-Gaspera, Tahar Bouceba, Fannie Semprez, Claire Legay, and Alexandre Dobbertin : J Biol Chem, 2023
• AChR β-Subunit mRNAs Are Stabilized by HuR in a Mouse Model of Congenital Myasthenic Syndrome With Acetylcholinesterase Deficiency.
  Karmouch J, Delers P, Semprez F, Soyed N, Areias J, Bélanger G, Ravel-Chapuis A, Dobbertin A, Jasmin BJ, Legay C : Front Mol Neurosci, 2020
• Collagens at the vertebrate neuromuscular junction, from structure to pathologies.
  Legay C, Dobbertin A : Neurosci Lett, 2020
• Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.
  Sigoillot SM, Bourgeois F, Karmouch J, Molgó J, Dobbertin A, Chevalier C, Houlgatte R, Léger J, Legay C : FASEB J, 2016
• MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance.
  Messéant J, Dobbertin A, Girard E, Delers P, Manuel M, Mangione F, Schmitt A, Le Denmat D, Molgó J, Zytnicki D, Schaeffer L, Legay C, Strochlic L : J Neurosci, 2015
• Developmental consequences of the ColQ/MuSK interactions
  Karmouch J, Dobbertin A, Sigoillot S, Legay C : Chem Biol Interact, 2013
• Existence of tenascin-C isoforms in rat that contain the alternatively spliced AD1 domain are developmentally regulated during hippocampal development
  Garwood J, Theocharidis U, Calco V, Dobbertin A, Faissner A : Cell Mol Neurobiol, 2012
• Analysis of combinatorial variability reveals selective accumulation of the fibronectin type III domains B and D of tenascin-C in injured brain.
  Dobbertin A, Czvitkovich S, Theocharidis U, Garwood J, Andrews MR, Properzi F, Lin R, Fawcett JW, Faissner A : Exp Neurol, 2010
• Contributions of selective knockout studies to understanding cholinesterase disposition and function
  Camp S, Zhang L, Krejci E, Dobbertin A, Bernard V, Girard E, Duysen EG, Lockridge O, De Jaco A, Taylor P : Chem Biol Interact, 2010
• Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-rich membrane anchor subunit and the attachment domain on the catalytic subunit.
  Dobbertin A, Hrabovska A, Dembele K, Camp S, Taylor P, Krejci E, Bernard V : J Neurosci, 2009
• Identification of cis-acting elements involved in acetylcholinesterase RNA alternative splicing.
  Guerra M, Dobbertin A, Legay C : Mol Cell Neurosci, 2008
• Evidence for distinct leptomeningeal cell-dependent paracrine and EGF-linked autocrine regulatory pathways for suppression of fibrillar collagens in astrocytes.
  Heck N, Garwood J, Dobbertin A, Calco V, Sirko S, Mittmann T, Eysel UT, Faissner A : Mol Cell Neurosci, 2007
• DSD-1-Proteoglycan/Phosphacan and receptor protein tyrosine phosphatase-beta isoforms during development and regeneration of neural tissues.
  Faissner A, Heck N, Dobbertin A, Garwood J : Adv Exp Med Biol, 2006
• Cholinesterases and the resistance of the mouse diaphragm to the effect of tubocurarine.
  Nguyen-Huu T, Dobbertin A, Barbier J, Minic J, Krejci E, Duvaldestin P, Molgó J : Anesthesiology, 2005
• The extracellular matrix glycoprotein Tenascin-C is expressed by oligodendrocyte precursor cells and required for the regulation of maturation rate, survival and responsiveness to platelet-derived growth factor.
  Garwood J, Garcion E, Dobbertin A, Heck N, Calco V, ffrench-Constant C, Faissner A : Eur J Neurosci, 2004
• Regulation of RPTPbeta/phosphacan expression and glycosaminoglycan epitopes in injured brain and cytokine-treated glia.
  Dobbertin A, Rhodes KE, Garwood J, Properzi F, Heck N, Rogers JH, Fawcett JW, Faissner A : Mol Cell Neurosci, 2003
• Activation of ionotropic glutamate receptors reduces the production of transforming growth factor-beta2 by developing neurons.
  Dobbertin A, Gervais A, Glowinski J, Mallat M : Eur J Neurosci, 2000
• Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2.
  Fidler PS, Schuette K, Asher RA, Dobbertin A, Thornton SR, Calle-Patino Y, Muir E, Levine JM, Geller HM, Rogers JH, Faissner A, Fawcett JW : J Neurosci, 1999
• Identification of CSF-1 as a brain macrophage migratory activity produced by astrocytes.
  Calvo CF, Dobbertin A, Gelman M, Glowinski J, Mallat M : Glia, 1998
• Neurons promote macrophage proliferation by producing transforming growth factor-beta2.
  Dobbertin A, Schmid P, Gelman M, Glowinski J, Mallat M : J Neurosci, 1997
• Migration and proliferation of mononuclear phagocytes in the central nervous system.
  Mallat M, Calvo CF, Dobbertin A : Adv Exp Med Biol, 1997
• Recruitment of brain macrophages: roles of cytokines and extracellular matrix proteins produced by glial or neuronal cells.
  Mallat M, Calvo CF, Dobbertin A : Braz J Med Biol Res, 1996
• Cor triatriatum dexter in an adult diagnosed by transesophageal echocardiography: a case report.
  Dobbertin A, Warnes CA, Seward JB : J Am Soc Echocardiogr, 1995
• Immunohistochemical detection of thrombospondin in microglia in the developing rat brain.
  Chamak B, Dobbertin A, Mallat M : Neuroscience, 1995
• Isolated in-vitro perfusion of pig hearts obtained from the abattoir: an alternative to animal experiments?
  Görge G, Erbel R, Dobbertin A, Hänggi M, Hake U, Meyer J : Eur Heart J, 1994
• Downregulation of in vitro neurotoxicity of brain macrophages by prostaglandin E2 and a beta-adrenergic agonist.
  Théry C, Dobbertin A, Mallat M : Glia, 1994